How To Predict Breast Cancer Relapse?

Scientists from Cambridge and Stanford universities have performed the research that shows breast cancer can be subcategorized into 11 separate types.

The hope is that by identifying the subtypes of breast cancer it could facilitate risk estimation of its reoccurrence, as various types have a difference chance of relapse. Some categories have a tendency of reoccurrence within 10 years after the initial diagnosis, while the others are not likely to come back. This becomes highly important as the findings could potentially ensure closer monitoring of those who are at the higher risk.

GCT has completed numerous cancer studies, including breast cancer clinical trials. We look forward to further promising updates on the research.

 

Source: Nature Journal 

Begin with Sleep

March 10th to 16th is also marked as the Sleep Awareness Week. It is organized by the National Sleep Foundation annually.

Getting enough of sleep and following sleep schedule is a crucial part of a healthy lifestyle. It facilitates cell regeneration, healing processes, and metabolism. If an optimal sleeping schedule is not followed, it can cause or contribute to weakening of the immune system, depression, and weight problems.

It is recommended for adults to receive from 7 to 9 hours of sleep daily, and to go to bed before midnight. It is also important to sleep in complete darkness to facilitate the generation of the melatonin hormone.

Here are some interesting facts about sleep according to National Sleep Foundation:

You Can Jolt Yourself Awake

It’s not unusual to feel like you’re physically falling while you’re falling asleep. This feeling can trigger your limbs to jolt yourself awake. Your body is typically temporarily paralyzed while you’re sleeping, but the paralysis hasn’t happened yet during the earliest, lightest sleep stage, so you might experience what is known as a hypnagogic.

Sleep is As Important as Diet and Exercise

You probably already fit in 30 minutes of exercise on most days and stock your kitchen with nutritious eats, but don’t forget to add “make time for zzz’s” to your stay-healthy list. It’s just as critical, because sleep deprivation has been linked to heart disease, depression, and diabetes. While you sleep, your body releases growth hormones that work to rebuild muscles and joints. The more sleep you get, the better equipped your body will be to repair itself.

You Have Dreams Even If You Don’t Remember Them

The average person has four to six dreams a night, but most people can’t recall up to 99 percent of them. Try keeping a dream journal next to your bed and jotting down anything that you remember as soon as you wake up.

You Can Sleep Your Way Skinny

Getting your beauty sleep can help regulate hormones that control appetite, so you’ll eat fewer calories overall when you snooze for seven to nine hours per night, compared with when you’re underslept. Specifically, lack of sleep can decrease ghrelin, a hormone that helps you feel satiated, and increase the hunger hormone leptin. Moreover, not sleeping enough makes you more likely to reach for unhealthy foods: Cravings for high-calorie, fatty foods surge by 45 percent when you’re sleep-deprived.

Certain foods contain an amino acid called tryptophan more available to the brain , which is why carbohydrate-heavy meals  can make you drowsy.

Newborns Sleep an Average of 14 to 17 Hours a Day

Babies have a lot of growing to do, so they need a lot more sleep than adults. The weird thing is that, unlike adults, if your baby is sleep-deprived he or will sleep less, not more!

Snoozing Can Improve Your Memory

Feeling more forgetful? Try clocking more time in the sack. In fact, sleep-deprived people score lower on tests of working memory (a.k.a. short-term memory) than those who have had a good night’s rest. Cerebral spinal fluid is pumped more quickly throughout the brain while you sleep. It acts like a dishwasher, whisking away waste products that brain cells make. So you wake up with, quite literally, a clean slate.

Athletes Need More Sleep

How much sleep that you need, exactly, depends on your genes. Most adults need about seven to nine hours a night, but athletes may improve their performance by sleeping up to 10 hours per night, because all of that physical activity means that their bodies require more sleep to repair muscles and restore energy.

Happy Birthday to Iryna Golovach!

Today we are celebrating the birthday of Iryna Golovach! Iryna is our CRA in the Ukrainian office. She’s been with GCT since 2008, and monitored numerous studies in Oncology, Women’s Health, Pediatrics, CNS and other fields.

All of us here at GCT wish Iryna a happy birthday! We hope this year will bring you a lot of happiness, many smiles, new achievements, and more exciting moments! Have a wonderful day 🙂

-GCT Team

GCT welcomes another New Team Member

As of March 2019 Jessica Goldenberg, M.S. joined GCT as a Project Manager for the U.S. Operations.

Jessica brings over 15 years of expertise working in the diverse settings of academic, hospital, CRO, and Pharmaceutical companies. She has experience in a variety of therapeutic areas, including Psychiatry, Neurology, Pain, Oncology, Dermatology, Cardiology, Gastroenterology, Infectious Diseases, Urology, Ophthalmology, Pediatrics, Respiratory and Rare Diseases.

Jessica completed her Master’s Degree in Regulatory Affairs / Quality Assurance with a focus on clinical trial management. She will be based in GCT headquarters in Princeton, New Jersey.

We are delighted to welcome Jessica to our global team!

GCT President at OCT Israel

GCT President, Dr. Jeffrey Apter is currently in Tel Aviv participating in the Outsourcing Clinical Trials (OCT) annual conference. Among the main objectives of the event are ensuring efficiency of clinical studies and good outsourcing strategies.

The conference is attended by biotech, pharmaceutical and medical device companies within Israel, which makes it an exciting networking opportunity for industry professionals.

If you are also attending OCT this year, please do not hesitate to contact us, and we will set up a meeting to chat about our opportunities for mutually beneficial partnership.

Looking forward to seeing you at OCT!

Brain Injury Awareness Month

 

The month of March is marked as the Brain Injury Awareness month. First started by Brain Injury Association of America (BIAA), today it has become huge around the world. The theme of the current campaign (2018-2020) is “Change Your Mind”.

Spreading awareness about Brain Injury is highly important. It helps understand what are the risks and effects of various brain injures. However, the most important goal is understanding the needs of those with brain injuries.

GCT believes together we can destigmatize brain injury, offer support to people living with brain injures, and empower their caregivers.

World Glaucoma Week

March 10th – 16th is the World Glaucoma Week. The event has been organized by World Glaucoma Association and Glaucoma Patient Association. Glaucoma is the third leading cause of blindness worldwide. In 2015 alone, approximately 3 million people became blind due to this devastating disease.

Global Clinical Trials is proud to participate in the fight for improving old and developing new treatment options for glaucoma and other diseases of the eye. Our team has conducted numerous glaucoma studies over the past 18 years, presently conducting a trial aimed at primary open angle glaucoma.

You can access valuable information regarding the awareness week on the World Glaucoma Week website.

 

Happy International Women’s Day!

Today we celebrate all the amazing Women who work at GCT! We recognize and appreciate every and each of you and your determination to work. Let your days be accompanied by success, love, care and beauty!

GCT President at GAP Conference

Last week Dr. Jeffrey Apter, GCT President took part in the Site Optimization Conference organized by Global Alzheimer’s Platform Foundation (GAP). Conference goal was for participants to exchange strategies on finding a cure for Alzheimer’s disease. Among the attendees were renowned Researchers, Sponsors, CROs and Investigative Sites from across the United States and Canada. One of the conference’s main topics was the importance of “Healthy living” for maintaining both physical and mental health.

Dr. Apter has more than 40 years of experience in the field of Psychiatry, and has been involved in clinical research for almost 30. He provided oversight and participated as a PI in close to 300 clinical trials in USA, Eastern Europe and Russia. The conference was a great opportunity for the field professionals to share their knowledge for the ultimate research progress.

February 28th: Rare Disease Day

First launched by EURORDIS (The Voice of Rare Disease Patients in Europe) in 2008, Rare Disease Day takes place on the last day of February every year.

A disease is considered rare if it affects fewer than 1 in 2 000 000 people (for the US). Rare diseases tend to not get as much publicity as, for example, various types of cancer or heart diseases. Still, they have a dramatic effect on lives of the sufferers, 50% of whom are children.

Due to the fact that these diseases are very diverse and uncommon, their research and treatment become challenging. In most cases, the studies need to be conducted on the international level to gather the most thorough and accurate data. Because the symptoms can easily be mistaken with the ones for other diseases, these studies also require professionals with the most extensive expertise.

GCT is proud to be responsible for managing a number of rare disease trials over the 17 years that we’ve been in business. Our goal is that people with rare diseases all around the world can receive the needed care and attention. Spread the information, so that we are more aware of rare diseases, and therefore more willing and capable of helping patients suffering from them.

Rare Disease Project in Russia

A multi-center rare disease Phase 3b clinical trial has been recently awarded to GCT. Managed globally by our long term Spanish CRO partner, the study will be also conducted at 2 clinical sites selected in Russia. New trial is designed to assess the safety and the efficacy of the innovative treatment for rare metabolic condition.

Eating Disorders Awareness Week

Today, Monday the 25th is the beginning of the Eating Disorders Awareness Week.

Raising awareness about eating disorders is crucial. According to World Health Organization, eating disorders have the highest mortality rate of any mental illness. Statistically, only one in ten sufferers will seek and receive treatment. Today, there are numerous hotlines created for people suffering from eating disorders. However, embarrassed of their problem and afraid of being stigmatized, many are hesitant to ask for help.

Let’s fight the stereotypes about eating disorders and learn more about them today, so we and our children can have healthier, happier and longer lives tomorrow!

 

 

Cardiac Study Expansion in Russia

GCT is happy to announce the expansion of the Phase III Cardiac Surgery Study in Russia. It is an international study aiming to recruit over 1000 patients worldwide. GCT Russian team is managing regulatory, clinical, and logistics part of the trial. Since 2017 and up until now 1 site from Russia was participating in this multi-national trial sponsored by EU Pharma company, now it will be conducted at 5 Russian sites in total.

66 Years Ago Today…

Today we are celebrating a huge milestone in scientific advances! 21th of February 1953 was marked by the discovery of the double helix, the twisted-ladder structure of deoxyribonucleic acid (DNA). James Watson and Francis Crick, the scientist were awarded the Nobel Prize in medicine for their discoveries.

 

Dr. Apter Attends ISCTM Scientific Meeting

GCT President, Dr. Apter will participate at the ISCTM 15th Annual Scientific Meeting this week. The event will take place in Washington, DC on February 19-21. During the conference, the attendees will discuss current challenges in CNS drug development, strategies for effective data management, as well as other subjects associated with clinical trials and methodology.

GCT looks forward to sharing our knowledge and experience in this challenging yet exciting area of study.

Happy Birthday to Elizaveta Medvedeva!

Today is the birthday of Elizaveta Medvedeva, GCT newest Business Development team member! We wish Elizaveta to enjoy the adventure of entering clinical trials field and to feel great support amongst colleagues at GCT.

Dear Elizaveta, have a wonderful, healthy, fun and exciting year! Happy Birthday!

 

International Epilepsy Day 2019

Neurologic disorders are the leading cause of death and disability in the world. The number of people suffering from them has increased dramatically over the past 25 years. According to the Neurological disorders: Public health challenges report from WHO, nearly 1 billion people worldwide suffer from various neurological disorders, and 50 million suffer from epilepsy.

International Epilepsy Day is celebrated every year on the second Monday of February. It is organized by International Beruea of Epilepsy and League Against Epilepsy, and it aims to promote awareness about the disorder.

Since 2001, GCT has been actively participating in CNS studies. We have gained a substantial experience in clinical trials for numerous neurological disorders. Among them are multiple Phase I-IV studies in Multiple Sclerosis, Alzheimer’s Disease, Schizophrenia and Acute Ischemic Stroke. For example, we recently have completed a Phase IIb and a Phase III trials for resistant partial-onset seizures (Epilepsy) for a US pharma. Both GCT President, Dr. Jeffrey Apter and CEO, Dr. Eugene Selivra are psychiatrists with 25+ years of experience in the CNS field.

Here at GCT we hope that new clinical studies will deliver more effective methods of coping with Epilepsy and other nervous system disorders.

Database Locked for the Women’s Health Study

We are glad to announce that the database for the Phase III Women’s Health Study was locked on February 4th after 7 years of trial duration. This is a multi-center, randomized, double-blind study conducted in patients with a previous preterm delivery, for its further prevention. GCT is proud to be managing this trial in Russia, Ukraine, Bulgaria, Hungary and Czech Republic, with a total of 1018 patients randomized in our countries.

GCT would like to thank every one of our team members, that worked hard to achieve this milestone!

 

And the Winner is…

We just had a raffle at GCT booth for our friends at DIA Europe 2019. Making the most of the conference, Christoffer von Sehested the lucky winner received a really special prize!

Greetings from GCT Team at DIA Europe

It is the last day of the DIA Europe 2019! While enjoying the productive and friendly atmosphere of the conference, do not miss a chance to stop by our booth #B14 and learn how to improve recruitment and data quality by choosing the right partner CRO and the right region for your clinical trial.

GCT team is currently attending the 3-day conference that takes place in Vienna. Dr. Selivra, CEO, Aleksandr Stiblo, Deputy Director Business Development, and Yuliya Pavlenko, Project Manager are sharing their knowledge and connecting with prospective partners.

We look forward to meeting with you!

 

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